Soprano Mirella Hagen studied in Karlsruhe with Prof. Christiane Hampe and in Stuttgart with Prof. Ulrike Sonntag, with whom she continues to work closely after graduation. She completed her diploma examinations in vocal performance and song interpretation (Prof. Cornelis Witthoefft) with distinction and in the soloist class with top marks. Master classes with KS Edith Mathis, Prof. Ulf Bästlein and Charles Spencer, as well as KS Helen Donath and Helmut Deutsch complemented her studies.

Already at the beginning of her studies she was supported by the Studienstiftung des deutschen Volkes, the Yehudi Menuhin Live Music Now Stiftung and the Richard Wagner Verband Stuttgart. She was a prizewinner at Jugend musiziert, the University Competition, the Paula Salomon Competition and a finalist at the International Hugo Wolf Competition Stuttgart and has received several awards for her Lied interpretations, including the Thomas Wiese Förderpreis and the Trude Eipperle Rieger Prize and the Förderpreis of the Hugo Wolf Competition in Slovenj Gradec (Slovenia).

After her studies, Mirella Hagen was engaged in the opera studio at the Stuttgart State Opera, where she sang roles such as Ännchen (Freischütz). At the Theater Regensburg she sang roles such as Gretel (Hänsel und Gretel), and at the Belgian Opera Vlaanderen as Anna (Nabucco) and Papagena (Die Zauberflöte). There she also sang the 1st Squire and the 1st Flower Girl in the Opera Award-winning production of Parsifal (directed by Tatjana Gürbaça), which was named Production of the Year. Further engagements took her to the Dortmund Opera and the Komische Oper Berlin.

At the Staatstheater Braunschweig she made her debut with great success as Adina (L'elisir d'amore) and Pamina (Die Zauberflöte), and also as Eliza Doolittle (My Fair Lady). She also sang lyric roles such as Gilda (Rigoletto) and Fiorella (Les Brigants) as well as the soprano part in the Brahms Requiem.In the summer of 2013, she made her internationally acclaimed debut at the Bayreuth Festival as Woglinde in "Rheingold" and "Götterdämmerung" as well as Waldvogel in "Siegfried" (directed by Castorf and conducted by Petrenko) and was invited back for the 2014 and 2015 festivals.

In April 2015, under Sir Simon Rattle, she sang Woglinde in the concert performances of Rheingold in the Herkulessaal of the Residenz in Munich with the Bavarian Radio Symphony Orchestra. The concert recording has been released on CD by BR Klassik.

In the fall of 2016, she made her debut at the Theater an der Wien with great success as Betty in Salieri's "Falstaff" under the baton of René Jacobs, with whom she toured Monteverdi's "Il ritorno d'Ulisse" and the Belgian B'Rock Orchestra to Brussels, Amsterdam, Cologne and Vienna in the spring of 2017. She made another tour with René Jacobs and the Freiburg Baroque Orchestra with "Le nozze di Figaro" to South Korea, China and Austria. She was heard as Pamina (Die Zauberflöte) at the Belgian Opera Vlaanderen and performed "Jauchzet Gott in allen Landen" and "Exsultate, jubilate" again with the Belgian orchestra B'Rock in France in May 2018. In January 2018, Mirella Hagen made her debut as Waldvogel (Siegfried) at the Bavarian State Opera under Kirill Petrenko. Mirella Hagen celebrated a great success as Morgana in Handel's opera "Alcina" in the fall of the same year at the Theater an der Wien conducted by Stephan Gottfried with the Concentus Musicus. She made her debut with the Waldvogel (Siegfried) in February 2019 at the Grand Théâtre Genève under the direction of Georg Fritzsch for the reopening of the opera house. In April 2019, the soprano will make her debut at the Graz Opera with Haydn's "Seasons" and later with Pamina at the Semperoper Dresden.

In addition to her operatic activities, the versatile artist is also in demand as a concert singer. She has worked closely with Helmuth Rilling, with whom she has traveled to Korea, Poland, Milan and Moscow and performed at the Beethovenfest Bonn, the European Music Festival Stuttgart and the Bachwoche Stuttgart. Under his direction she sang the "Exsultate, Jubilate" , the Soprano I of the "C minor Mass" by Mozart, the "Magnificat", sacred cantatas and the "St. Matthew Passion" by Bach. At the Belgian Opera Vlaanderen, Mirella Hagen also performed the Soprano I in Mozart's "C minor Mass" under the musical direction of Umberto Benedetti Michelangeli. Under Hans-Christoph Rademann, she sang the St. John Passion at the Polish Philharmonic in Katowice and performed this piece again in March 2018 at the Tonhalle in Zurich.

Another focus in her still young career is lieder singing. Together with pianist Kerstin Mörk, she has performed at many major lied venues, including the Villa Wahnfried and the Hugo Wolf Academy in Stuttgart and the Ljubljana Festival. In 2016, the two musicians released their debut CD "Mädchenherzen" with songs by Richard Strauss, Ludwig Thuille and Hugo Wolf on the GENUIN label, which was enthusiastically received internationally.