worked for many years with London's leading period instrument ensembles, such as The English Baroque Soloists, The Academy of Ancient Music, English Concert and Orchestre Revolutionnaire et Romantique. She has performed in the major concert halls, at international festivals throughout Europe, the USA, and Japan and has participated in over 100 CD recordings. She has performed as soloist and concertmaster with Musica Antiqua Köln in 2000, Das Neue Orchester 2001-2004 and has been concertmaster with The Academy of Ancient Music since 1999. Furthermore, she has been engaged as concertmaster and coach for historical performance practice with the Orchestra of the Frankfurt Opera and Theaterorchester der Stadt Aachen.

Her long-standing association with the Royal Northern College of Music, Manchester as tutor for baroque violin and historical performance practice demonstrates her passion for teaching. She has directed the Royal Northern College of Music Baroque Orchestra since 2005. In the winter semester of 2005, she began her teaching career at the Hochschule für Musik, Würzburg, where she teaches a full baroque violin class.

Pauline Nobes has lectured at international summer courses in Jerusalem and Dartington, among other places. She has been engaged by the Mannheim Orchestra Academy as concertmaster and coach, and by the European Union Baroque Orchestra on several occasions as soloist and concertmaster. This summer she is teaching at the Summer Academy in Neuburg.

In 2001 Pauline Nobes received her doctorate with her thesis on the repertoire for unaccompanied solo violin before 1750 with special attention to string technical aspects. A solo CD and editions of her self-published works document her research activities.

Unusually, Pauline Nobes began her career as a brass player. She obtained an ARCM diploma in trumpet at the age of seventeen and recorded the trumpet solo in Beethoven's Leonore with Sir John Eliot Gardiner after concerts in Salzburg and New York, among others, which were met with loud applause.